兰雨，研究员，博士生导师。“国家高层次人才计划”入选者、“珠江人才计划”领军人才。成果曾获《国家自然科学二等奖》（2012）、入选《中国2020年度重要医学进展》、《2022 Sanofi-细胞研究杰出论文奖》、《国家“十三五”科技创新成就展》、《中国血液学年度十大研究进展》(2020/2021/2022/2024)。承担国家重点研发计划课题、国家自然科学基金重大项目课题等项目。
      院校引进人才，2025年加入院校，曾任暨南大学血液学研究所所长、再生医学教育部重点实验室副主任。

研究方向聚焦血管与造血系统发育的谱系规律及调控机制。系列研究揭秘哺乳动物胚胎血管及造血系统的异质性细胞群体及发育路径、发现胚胎最早和广泛发生的静脉动脉命运转换、揭示造血干细胞形成的系列调控新机制。通讯作者（含共同）研究论文发表在Nature、Cell Stem Cell、Cell Res(x5)、Dev Cell(x2)、Immunity、Nat Immunol、Blood(x2)等高水平期刊。其中3篇封面论文、5篇被F1000推荐、6篇获同期专文评述、1篇ESI高被引论文。

1．Haizhen Wang#, Di Liu#, Haifeng Chen#, Yuqing Jiao, Haixin Zhao, Zongcheng Li, Siyuan Hou, Yanli Ni, Rong Zhang, Jinyong Wang, Jie Zhou*, Bing Liu*, Yu Lan*. Nupr1 Negatively Regulates Endothelial to Hematopoietic Transition in the Aorta-Gonad-Mesonephros Region. Adv Sci. 2023 Feb;10(6):e2203813. (IF2023=14.13)

2．Siyuan Hou#, Zongcheng Li#, Ji Dong#, Yun Gao#, Zhilin Chang#, Xiaochen Ding#, Shuaili Li, Yunqiao Li, Yang Zeng, Qian Xin, Baihan Wang, Yanli Ni, Xiaowei Ning, Yuqiong Hu, Xiaoying Fan, Yu Hou, Xianlong Li, Lu Wen, Bin Zhou, Bing Liu*, Fuchou Tang*, Yu Lan*. Heterogeneity in endothelial cells and widespread venous arterialization during early vascular development in mammals. Cell Res. 2022 Apr;32(4):333-348. (IF2022=44.1, 同期专文评述)

3．Xianlong Li#, Di Liu#, Linlin Zhang, Haizhen Wang, Yunqiao Li, Zongcheng Li, Aibin He, Bing Liu, Jie Zhou*, Fuchou Tang*, Yu Lan*. The comprehensive DNA methylation landscape of hematopoietic stem cell development. Cell Discov. 2021 Sep 21;7(1):86. (IF2021=38.079)

4．Zhilei Bian#, Yandong Gong#, Tao Huang#, Christopher Z. W. Lee#, Lihong Bian#, Zhijie Bai#, Hui Shi#, Yang Zeng, Chen Liu, Jian He, Jie Zhou, Xianlong Li, Zongcheng Li, Yanli Ni, Chunyu Ma, Lei Cui, Rui Zhang, Jerry K. Y. Chan, Lai Guan Ng, Yu Lan*, Florent Ginhoux*, Bing Liu*. Deciphering Human Macrophage Development at Single Cell Resolution. Nature. 2020 Jun;582(7813):571-576. (IF2020=49.962, F1000, ESI高被引论文, C100)

5．Siyuan Hou#, Zongcheng Li#, Xiaona Zheng#, Yun Gao#, Ji Dong#, Yanli Ni#, Xiaobo Wang, Yunqiao Li, Xiaochen Ding, Zhilin Chang, Shuaili Li, Yuqiong Hu, Xiaoying Fan, Yu Hou, Lu Wen, Bing Liu*, Fuchou Tang*, Yu Lan*. Embryonic endothelial evolution towards first hematopoietic stem cells revealed by single-cell transcriptomic and functional analyses. Cell Res. 2020 May;30(5):376-392. (IF2020=25.617, 同期专文评述)

6．Yang Zeng#, Chen Liu#, Yandong Gong#, Zhijie Bai#, Siyuan Hou#, Jian He, Zhilei Bian, Zongcheng Li, Yanli Ni, Jing Yan, Tao Huang, Hui Shi, Chunyu Ma, Xueying Chen, Jinyong Wang, Lihong Bian, Yu Lan*, Bing Liu*, Hongbo Hu*. Single-Cell RNA Sequencing Resolves Spatiotemporal Development of Pre-thymic Lymphoid Progenitors and Thymus Organogenesis in Human Embryos. Immunity. 2019 Nov 19;51(5):930-948.e6. (IF2019=22.553, 同期专文评述)

7．Yang Zeng#, Jian He#, Zhijie Bai#, Zongcheng Li#, Yandong Gong, Chen Liu, Yanli Ni, Junjie Du, Chunyu Ma, Lihong Bian, Yu Lan*, Bing Liu*. Tracing the first hematopoietic stem cell generation in human embryo by single-cell RNA sequencing. Cell Res. 2019 Nov;29(11):881-894. (IF2019=20.507, F1000, C100)

8．Jie Zhou#, Jiayue Xu#, Linlin Zhang#, Siqi Liu#, Yanni Ma#, Xin Wen, Junkai Hao, Zongcheng Li, Yanli Ni, Xianlong Li, Fan Zhou, Qingqing Li, Fang Wang, Xiaoshuang Wang, Yanmin Si, Pengcheng Zhang, Chen Liu, Marisa Bartolomei, Fuchou Tang, Bing Liu*, Jia Yu*, Yu Lan*. Combined single-cell profiling of lncRNAs and functional screening reveals H19 is pivotal for embryonic hematopoietic stem cell development. Cell Stem Cell. 2019 Feb 7;24(2):285-298.e5. (IF2019=20.860, F1000)

9．Hui Ye#, Xiaobo Wang#, Zongcheng Li, Fan Zhou, Xianlong Li, Yanli Ni, Weijing Zhang, Fuchou Tang, Bing Liu*, Yu Lan*. Clonal analysis reveals remarkable functional heterogeneity during hematopoietic stem cell emergence. Cell Res. 2017 Aug;27(8):1065-1068. (IF2017=15.393, F1000)

10．Fangfei Li#, Yu Lan#,*, Youliang Wang#, Jun Wang, Guan Yang, Fanwei Meng, Hua Han, Anming Meng, Yaping Wang, Xiao Yang*. Endothelial Smad4 maintains cerebrovascular integrity by activating N-cadherin through cooperation with Notch. Dev Cell. 2011 Mar 15;20(3):291-302. (IF2011=14.03, 同期专文评述, F1000, C100)